Housed in a 1849 train station, the museum features a permanent exhibition that addresses Baltimore during the Civil War and the part that the President Street Station played in this era, Maryland's railroad history and the building's role in the transportation of slaves escaping to the North.

Tour the Evergreen House and the Homewood House Museum featuring exhibits detailing life of early 19th century Baltimore.

The Baltimore & Ohio Railroad Museum is dedicated to the preservation and interpretation of American railroading through the history and legacy of the Baltimore and Ohio Railroad, the Chesapeake and Ohio Railway, the Western Maryland Railway, and the regional railroads of the mid-Atlantic.